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Life uses 4 DNA letters. Scientists just made 8 work
SCIENCE
www.sciencedaily.com
27d ago • 2 min read

Life uses 4 DNA letters. Scientists just made 8 work


AI KEY TAKEAWAYS (TL;DR)
  • Researchers at UC San Diego have demonstrated that a key cellular enzyme can accurately read an eight-letter genetic alphabet, doubling the four letters used by all known life on Earth
  • Detailed imaging revealed that RNA polymerase handles synthetic DNA letters in surprisingly similar ways to natural ones
  • The finding brings scientists closer to building expanded genetic systems that could perform entirely new biological functions

Why it matters: Highlights progress and positive advancements shaping a better world.

Researchers at UC San Diego have demonstrated that a key cellular enzyme can accurately read an eight-letter genetic alphabet, doubling the four letters used by all known life on Earth. Detailed imaging revealed that RNA polymerase handles synthetic DNA letters in surprisingly similar ways to natural ones. The finding brings scientists closer to building expanded genetic systems that could perform entirely new biological functions.

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